Burgeon
CALHYDRA is a multiple effect dermal filler application
kit that brings together the essential properties of subdermal
fillers in one product. Developed through the perfect harmony
of the biostimulator NOVUMA and REFREJ, it effectively provides
lifting and moisture to the skin.
CALHYDRA is a multiple effect dermal filler application kit that brings together the essential properties of subdermal fillers in one product. Developed through the perfect harmony of the biostimulator NOVUMA and REFREJ, it effectively provides lifting and moisture to the skin.


REFREJ is a low cross-linked HA (Hyaluronic Acid) that restores the skin's essential glow and moisture. While waiting for the full biostimulating effect of NOVUMA, the immediate effects of REFREJ ensure a seamless transition. As NOVUMA’s effects peak, REFREJ’s effects gradually diminish.

What Makes CALHYDRA Unique

Density Control:

CALHYDRA is the only product in the world where physicians can adjust the density, containing both CaHA (Calcium Hydroxyapatite) and HA (Hyaluronic Acid), based on the area of application.

NOVUMA and REFREJ Harmony:

It offers groundbreaking and guiding harmony in facial filler applications.

Instant Volume and Elasticity:

Enhances skin quality, providing a lifting and lost skin elasticity immediately.

Areas of Application

Nose

Cheeks

Nasolabial folds

Marionette lines

Cheekbones

Lower jaw

Chin

Neck*

Thighs*

Arms*

Hips*

Décolletage*

Abdomen*

Hands*

Knees*

*The licensing process is not yet complete. However, no adverse effects have been reported regarding off-label use to date. If planning to apply NOVUMA and REFREJ  to these areas, the patient must be thoroughly informed, and written “Informed Consent” must be obtained.

Areas of Application

Nose

Cheeks

Nasolabial folds

Marionette lines

Cheekbones

Lower jaw

Chin

Neck*

Thighs*

Arms*

Hips*

Décolletage*

Abdomen*

Hands*

Knees*

*The licensing process is not yet complete. However, no adverse effects have been reported regarding off-label use to date. If planning to apply NOVUMA to these areas, the patient must be thoroughly informed, and written “Informed Consent” must be obtained.