• Adaptation with the tissues by optimal degree of cross-linking
  • Ideal particle size minimizing the risk of nodule formation
  • Enhanced patient comfort with 0.3% lidocaine
  • Easy injection with an average syringe extrusion force of 3.2 N
  • Rehydration while filling superficial wrinkles
  • Cross-linking density compatible with middle dermis and lip vermilion border
  • Easily adjustable gel structure
  • Optimized cohesivity and elasticity that keeps the tissue compatible with its natural form
  • Comfortable injection experience with an average syringe extrusion force of 3.3 N
  • Natural results in lip contour and augmentation
  • High performance for correction of superficial wrinkles
  • Iona® is developed to treat the middle face and cheeks; corrects deep wrinkles, deep marionette lines, and deep nasolabial folds and volumizes the lips.
  • High performance and sustained effect on the lips.
  • Effective results in augmentation with moderate-to-high lifting capacity.
  • Patient comfort with 0.3% lidocaine.
  • Easy application with an average syringe extrusion force of 3.6 N.
  • Predictable injection experience with homogeneous filler distribution.
  • Dora® is designed for the treatment of facial contours, cheekbones, cheeks, jaw, and jawline.
  • It offers high-level performance and durability with its ideal particle size, cross-linking density, and rheological values.
  • The injection experience is comfortable for the physician with an average syringe extrusion force of 4 N.
  • The application provides comfort for the patient with 0.3% lidocaine
Corintha

Corintha® is used in superficial wrinkles, perioral and periorbital areas. Corintha® minimizes the risk of migration and nodule formation with low-to-moderate cohesivity and elasticity.

It offers balanced tissue restoration without creating a rough and nodular surface.

Its small particle size and cross-linking density are designed to ensure optimal biocompatibility.

  • Fine Balance Between the Necessity and Performance
  • Usage in a High Confidence Interval
  • Tissue-Mimetic Design™ for Ideal Tissue Compatibility
Tuscan

Tuscan® is designed to be in perfect synchronicity without distorting the natural movement of the lips and can be easily shaped by the physician.

Tissue-Mimetic Design™ facilitates homogenous spread in the tissue, maintaining the natural appearance of the lips after augmentation and contouring.

Developed to ensure optimal water retention capacity, Tuscan® maintains the ideal hydration level in the tissue.

The product can also be used in superficial wrinkles and therefore offers multiple treatment possibilities in varying areas.

  • Homogenous Distribution in the Tissue
  • Easily Shaped by the Physician
  • Multiple Application Areas
  • Regenerative Effect on Wrinkles & Maintenance of the Natural Shape of the Lips with the Tissue-Mimetic Design™
Iona

Displays high resistance to deformation created by facial expressions.

Provides natural and effective results in volume restoration

Tissue-Mimetic Design™ offers the desired results on the lips and minimizes the related risks

  • High Resistance to Dynamic Forces
  • Long Durability with Stable Structure
  • Minimum Risk and Maximum Performance on the Lips & Optimal Tissue Adaptation in Deep Wrinkles with Tissue-Mimetic Design™
  • High Compatibility & Effective Performance
Dora

Tissue-Mimetic Design™ minimizes the dispersion and migration of the product during facial muscle contractions.

Dora® exhibits a bulk structure and can therefore conform to the tissue in 3D contouring, volume projection, and definition.

The filler’s structure provides the ideal combination of durability and tissue compatibility.

It offers maximum performance with minimized side effects in medium and long term.

  • High Compatibility & Maximum Performance
  • Harmonized & Durable Effect
  • High Lifting Capacity in Confidence Interval
High-Technology
Production

Youth Series dermal fillers, which contain hyaluronic acid particles cross-linked with BDDE, are structured according to the rheological needs of the respective application area. With the PPB (Parts Per Billion) Purity Technology, measurements are made at the level of ppb, which is 1000 times below the ppm value determined by the FDA. In this way, the residual BDDE was reduced 20-fold below the limit recommended by the FDA with PPB measurement. The use of the filler in this confidence interval enhances its biocompatibility.

1 - Safe hyaluronic acid molecules derived from bacterial fermentation

2 - Stability & metabolic durability with effective BDDE use

3 - Optimal rheology designed for effective, safe, and stable application

Modern
Production
  • Production in cleanrooms under GMP Standards
  • Full compliance with European standards
  • Optimal rheological properties
  • Sterilization technology protecting the viscoelastic structure
  • Confirmed HA concentration
  • High purity with a specialized manufacturing process
  • Particle size designed specifically for the application area
  • Tissue-compatible osmolality balance
  • Optimal pH range
  • Easy application with low extrusion force
  • Lidocaine addition in confidence interval for patient comfort
  • High stability after application
Rheological Parameters &
Dynamic Forces Affecting Skin Tissue
Dermal fillers are exposed to many internal and external forces after injection to the subcutaneous plane. The filler is affected by the force of facial mimic muscles moving with a subsequent impact on the tissue as shear stress, stretching, torsion, and compression
Youth Support series is DESIGNED TO RESIST THESE FORCES WITHOUT DEFORMATION, AND TO MINIMIZE RISKS SUCH AS MIGRATION, NODULES, AND GRANULOMA BY MATCHING THE NATURAL LOOK and FEEL OF THE TISSUE.
Rheological Parameters &
Dynamic Forces Affecting Skin Tissue
Rheology examines the behavior of hyaluronic acid fillers subjected to shearing stress and stretching after being injected into the tissue and defines the physical properties of the fillers. The rheological parameters of the Youth Support hyaluronic acid series are measured with a rheometer device. Elastic modulus (G’) and cohesivity are calculated, which shows the ability of the cross-linked hyaluronic acid molecules to hold together
All Youth Support dermal fillers ARE DEVELOPED TO ADAPT TO THE ELASTICITY OF THE SKIN WITH THEIR VISCOELASTIC PROPERTIES.
Rheological Parameters &
Measurement of Elasticity Modulus (G’)
The elasticity modulus (G’) value indicates the durability of the fillers’ flexibility against internal and external forces after their subcutaneous administration. The G’ value represents how much the shape of the filler changes when subjected to these forces and informs about the lifting capacity
The Youth Support hyaluronic acid fillers ARE DESIGNED TO PROVIDE MAXIMUM PERFORMANCE BY MINIMIZING THE RISK OF NODULES AND PLASTIC APPEARANCE IN SHORT, MEDIUM, AND LONG TERM.
Rheological Parameters &
Measurement of Cohesivity
Cohesivity represents the ability of the cross-linked hyaluronic acid molecules to hold together when the filler is placed under the skin. When the face is subjected to external forces (such as a pillow or massaging etc.), the filler in the tissue is expected to spread evenly, with low-to-moderate and moderate-to-high cohesivity depending on the area of injected hyaluronic acid fillers
The cohesivity of Youth Support IS DEVELOPED TO ACHIEVE IDEAL TISSUE COMPATIBILITY AND TO MINIMIZE THE RISK OF FILLER MIGRATION IN THE AREAS WHERE IT IS INJECTED.
Rheological Parameters &
Cross-Linking Density
While the durability of the filler is supported by different cross-linking densities among the products in the Youth Support series, the physical properties of the fillers show a balanced correlation.
With the PPB (Parts Per Billion) Purity technology, measurements are made at the level of ppb, which is 1000 times below the ppm value determined by the FDA. In this way, the residual BDDE was reduced 20 times below the limit recommended by the FDA with ppb measurement. The use of the filler in this confidence interval enhances its biocompatibility
Rheological Parameters &
Innovative Production Method
Harmonophasic Technology™ With Harmonophasic Technology™, the cross-linked hyaluronic acid particle structures are uniformly distributed in the modified carrier phase. Tissue adaptation is maintained at the maximum level with the 20-fold decrease in the BDDE (butanediol diglycidyl ether) ratio, which is below the limit accepted by the FDA, using the technology involving PPB (Parts Per Billion) design.
This technology harmonizes biphasic and monophasic features. It is more cohesive when compared with other particulate structures exhibiting biphasic behaviour. Furthermore, it is more durable and stable compared to homogenous structures exhibiting monophasic behaviour.
Rheological Parameters &
A Unique Method Supporting Balance & Ideal Tissue Compatibility
Tissue-Mimetic Design™ defines the optimal tissue adaptation with a balanced combination of elasticity, cohesivity, and cross-linking density.
  • Does not interfere with the natural appearance of facial expressions
  • Rheological balance to minimize the risk of nodules and migration
  • Minimum tolerance for deformation against internal and external forces in the tissue
  • High performance by protecting the natural tissue structure
  • Minimized side effects in the short, medium, and long term
  • Ideal results in each area of injection
Rheological Parameters &
Osmolality Analysis
The plasma osmolality is examined to adjust the filler osmolality with the electrolyte-water balance within the body. The osmolality value indicates the oedema-inducing effect of fillers, and a high value means an increased risk of oedema.
All Youth Support products ARE DEVELOPED TO MINIMIZE THE RISK OF OEDEMA COMPARED TO THE LEADING PRODUCTS ON THE MARKET WITH AN OSMOLALITY VALUE OF 330 MOSM/KG.
Quality
Management

To focus on product needs in the market by following the developments in medicine and engineering,

To implement the quality service knowledge with the involvement of all the management functions and employees,

To provide customer, shareholder, and employee satisfaction to improve mutual liability,

To contribute to the health of patients and achievements of physicians by reviewing the feedback on surgical operations in which our products are applied,

To enable employees to take part in the success of the company and corporate cultural activities and to create a common identity with training targets,

To manufacture environment-friendly products by taking responsibility for social and ethical subjects

To develop products and technologies that are indispensable for human health, to manufacture with the most appropriate parameters, and to validate them under the best clinical conditions,

To fulfil the global regulatory requirements and the terms of the Quality Management System and to maintain the development of this system,

To constantly evaluate and develop the effectiveness of the current Quality Management System and the quality goals established in accordance with quality policies.

Clinical
Experiences

YS Series provides suitable extrusion force with high stability and ease of application after application.

YS Series allows you to have a successfull clinical effect with its particle size specially designed for various needs and usage areas for different application areas & tissue compatible osmolality balance.

Publications

E-MAIL

info@burgeon.me